Hydrophilically stabilized gold nanostars as SERS labels for tissue imaging of the tumor suppressor p63 by immuno-SERS microscopy

Autor(en): Schuetz, Max
Steinigeweg, Dennis
Salehi, Mohammad
Koempe, Karsten
Schluecker, Sebastian
Stichwörter: Chemistry; Chemistry, Multidisciplinary; NANOPARTICLES
Erscheinungsdatum: 2011
Herausgeber: ROYAL SOC CHEMISTRY
Journal: CHEMICAL COMMUNICATIONS
Volumen: 47
Ausgabe: 14
Startseite: 4216
Seitenende: 4218
Zusammenfassung: 
A biocompatible, seed-mediated synthesis of monodisperse similar to 60 nm gold nanostars, followed by hydrophilic stabilization with ethylene glycol-modified Raman reporter molecules, is presented. Their application as SERS labels for imaging of the tumor suppressor p63 in prostate biopsies by immuno-SERS microscopy is demonstrated.
ISSN: 13597345
DOI: 10.1039/c0cc05229a

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