Yeast on the milky way: genetics, physiology and biotechnology of Kluyveromyces lactis

Autor(en): Rodicio, Rosaura
Heinisch, Juergen J.
Stichwörter: A SYNTHETASE GENES; ACETYL-COENZYME; BETA-GALACTOSIDASE; Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology; FUNCTIONAL-CHARACTERIZATION; glucose signalling; GLUCOSE-TRANSPORTER GENE; heterologous gene expression; ISOCITRATE LYASE; lactose metabolism; MAPK signalling; Microbiology; MOLECULAR-GENETICS; Mycology; non-Saccharomyces yeast; SACCHAROMYCES-CEREVISIAE; SIGNALING PATHWAY; TRANSCRIPTIONAL REGULATION
Erscheinungsdatum: 2013
Herausgeber: WILEY
Journal: YEAST
Volumen: 30
Ausgabe: 5
Startseite: 165
Seitenende: 177
The milk yeast Kluyveromyces lactis has a life cycle similar to that of Saccharomyces cerevisiae and can be employed as a model eukaryote using classical genetics, such as the combination of desired traits, by crossing and tetrad analysis. Likewise, a growing set of vectors, marker cassettes and tags for fluorescence microscopy are available for manipulation by genetic engineering and investigating its basic cell biology. We here summarize these applications, as well as the current knowledge regarding its central metabolism, glucose and extracellular stress signalling pathways. A short overview on the biotechnological potential of K. lactis concludes this review. Copyright (c) 2013 John Wiley & Sons, Ltd.
ISSN: 0749503X
DOI: 10.1002/yea.2954

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