Browsing by Author Holthuis, Joost C. M.


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Issue DateTitleAuthor(s)
2019Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramidesKol, Matthijs; Williams, Ben; Toombs-Ruane, Henry; Franquelim, Henri G.; Korneev, Sergei ; Schroeer, Christian; Schwille, Petra; Trauner, Dirk; Holthuis, Joost C. M.; Frank, James A.
2019Osteoporosis and skeletal dysplasia caused by pathogenic variants in SGMS2Pekkinen, Minna; Terhal, Paulien A.; Botto, Lorenzo D.; Henning, Petra; Makitie, Riikka E.; Roschger, Paul; Jain, Amrita; Kol, Matthijs; Kjellberg, Matti A.; Paschalis, Eleftherios P.; van Lassen, Koen; Murray, Mary; Bayrak-Toydemir, Pinar; Magnusson, Maria K.; Jans, Judith; Kausar, Mehran; Carey, John C.; Somerharju, Pentti; Lerner, Ulf H.; Olkkonen, Vesa M.; Klaushofer, Klaus; Holthuis, Joost C. M.; Makitie, Outi
2022Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathwaySokoya, Tolulope; Parolek, Jan; Foged, Mads Moller; Danylchuk, I, Dmytro; Bozan, Manuel; Sarkar, Bingshati; Hilderink, Angelika; Philippi, Michael; Botto, Lorenzo D.; Terhal, Paulien A.; Makitie, Outi; Piehler, Jacob ; Kim, Yeongho; Burd, Christopher G.; Klymchenko, Andrey S.; Maeda, Kenji; Holthuis, Joost C. M.
2021Short Photoswitchable Ceramides Enable Optical Control of ApoptosisMorstein, Johannes; Kol, Matthijs; Novak, Alexander J. E.; Feng, Suihan; Khayyo, Shadi; Hinnah, Konstantin; Li-Purcell, Nasi; Pan, Grace; Williams, Benjamin M.; Riezman, Howard; Atilla-Gokcumen, G. Ekin; Holthuis, Joost C. M.; Trauner, Dirk
2019Sphingomyelin biosynthesis is critical in organizing phosphoinositide turnover during phagocytic uptake of Mycobacterium tuberculosisNiekamp, Patrick; Guzman, Gaelen; Leier, Hans C.; Rashidfarrokhi, Ali; Richina, Veronica; Pott, Fabian; Holthuis, Joost C. M.; Tafesse, Fikadu G.
2021Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell EntryNiekamp, Patrick; Guzman, Gaelen; Leier, Hans C.; Rashidfarrokhi, Ali; Richina, Veronica; Pott, Fabian; Barisch, Caroline ; Holthuis, Joost C. M.; Tafesse, Fikadu G.
2021Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell EntryNiekamp, Patrick; Guzman, Gaelen; Leier, Hans C.; Rashidfarrokhi, Ali; Richina, Veronica; Pott, Fabian; Barisch, Caroline ; Holthuis, Joost C. M.; Tafesse, Fikadu G.
2019Sphingomyelin is critical in organizing phosphoinositide dynamics during phagocytic uptake of Mycobacterium tuberculosisNiekamp, Patrick; Guzman, Gaelen; Leier, Hans C.; Rashidfarrokhi, Ali; Richina, Veronica; Holthuis, Joost C. M.; Tafesse, Fikadu G.
2014Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosisTafesse, Fikadu G.; Vacaru, Ana M.; Bosma, Elleke F.; Hermansson, Martin; Jain, Amrita; Hilderink, Angelika; Somerharju, Pentti; Holthuis, Joost C. M.
2016Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site engineering of sphingomyelin synthasesKol, Matthijs; Panatala, Radhakrishnan; Nordmann, Mirjana; Swart, Leoni; van Suijlekom, Leonie; Cabukusta, Birol; Hilderink, Angelika; Grabietz, Tanja; Mina, John G. M.; Somerharju, Pentti; Korneev, Sergei ; Tafesse, Fikadu G.; Holthuis, Joost C. M.
2017Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthasesKol, Matthijs; Panatala, Radhakrishnan; Nordmann, Mirjana; Swart, Leoni; van Suijlekom, Leonie; Cabukusta, Birol; Hilderink, Angelika; Grabietz, Tanja; Mina, John G. M.; Somerharju, Pentti; Korneev, Sergei ; Tafesse, Fikadu G.; Holthuis, Joost C. M.
2023Systematic analysis of the sphingomyelin synthase family in<i>C. elegans</i>Guzman, Gaelen; Farley, Scotland; Kyle, Jennifer; Bramer, Lisa; Hoeltzl, Sandra; van den Dikkenberg, Joep; Holthuis, Joost C. M.; Tafesse, Fikadu G.
2023Toxoplasma ceramide synthases: Gene duplication, functional divergence, and roles in parasite fitnessKoutsogiannis, Zisis; Mina, John G.; Albus, Christin A.; Kol, Matthijs A.; Holthuis, Joost C. M.; Pohl, Ehmke; Denny, Paul W.
2019Unraveling the molecular principles by which ceramides commit cells to deathDadsena, Shashank; Hassan, Dina G.; Holthuis, Joost C. M.
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