Piehler, Jacob

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Full Name
Piehler, Jacob
 
Variants
Piehler, J
Piehler, Jacob
 
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Country
Germany
 
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Publications


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101-120 von 154

ErscheinungsdatumTitelAutor(en)
1012020Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutationsWilmes, Stephan; Hafer, Maximillian; Vuorio, Joni; Tucker, Julie A.; Winkelmann, Hauke; Loechte, Sara; Stanly, Tess A.; Prieto, Katiuska D. Pulgar; Poojari, Chetan; Sharma, Vivek; Richter, Christian P.; Kurre, Rainer ; Hubbard, Stevan R.; Garcia, K. Christopher; Moraga, Ignacio; Vattulainen, Ilpo; Hitchcock, Ian S.; Piehler, Jacob 
1022020Engineered IL-10 variants elicit potent immuno-modulatory activities at therapeutic low ligand dosesGorby, Claire; J, Sotolongo Bellón; Wilmes, S.; Warda, Walid; Pohler, Elizabeth; Fyfe, Paul K.; Cozzani, Adeline; Ferrand, Christophe; Walter, M. Todd; Mitra, S.; Piehler, Jacob ; Moraga, Ignacio
1032020Tuning TPO-R signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemiaCui, Lu; Moraga, Ignacio; Lerbs, Tristan; Neste, Camille Van; Wilmes, Stephan; Tsutsumi, Naotaka; Trotman-Grant, Aaron Claudius; Gakovic, Milica; Andrews, Sarah; Gotlib, Jason; Darmanis, Spyridon; Enge, Martin; Quake, Stephen R.; Hitchcock, Ian S.; Piehler, Jacob ; Garcia, K. Christopher; Wernig, Gerlinde
1042020TIN2 facilitates TRF1-mediated trans- and cis-interactions on physiologically relevant long telomeric DNAPan, Hai; Kaur, Parminder; Liu, Ming; Xu, Pengning; Mahn, Chelsea; Barnes, Ryan P.; Tang, Qingyu; Hao, Pengyu; Bhattaram, Dhruv; You, Changjiang ; Piehler, Jacob ; Weninger, Keith; Riehn, Robert; Smith, Susan; Opresko, Patricia L.; Wang, Hong
1052021Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilizationStuber, Jakob C.; Richter, Christian P.; Bellon, Junel Sotolongo; Schwill, Martin; Konig, Iwo; Schuler, Benjamin; Piehler, Jacob ; Plueckthun, Andreas
1062021Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonistGlassman, Caleb R.; Su, Leon; Majri-Morrison, Sonia S.; Winkelmann, Hauke; Mo, Fei; Li, Peng; Perez-Cruz, Magdiel; Ho, Peggy P.; Koliesnik, Ievgen; Nagy, Nadine; Hnizdilova, Tereza; Picton, Lora K.; Kovar, Marek; Bollyky, Paul; Steinman, Lawrence; Meyer, Everett; Piehler, Jacob ; Leonard, Warren J.; Garcia, K. Christopher
1072021Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNAPan, Hai; Kaur, Parminder; Barnes, Ryan; Detwiler, Ariana C.; Sanford, Samantha Lynn; Liu, Ming; Xu, Pengning; Mahn, Chelsea; Tang, Qingyu; Hao, Pengyu; Bhattaram, Dhruv; You, Changjiang ; Gu, Xinyun; Lu, Warren; Piehler, Jacob ; Xu, Guozhou; Weninger, Keith; Riehn, Robert; Opresko, Patricia L.; Wang, Hong
1082021Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responsesWilmes, Stephan; Jeffrey, Polly-Anne; Martinez-Fabregas, Jonathan; Hafer, Maximillian; Fyfe, Paul K.; Pohler, Elizabeth; Gaggero, Silvia; Lopez-Garcia, Martin; Lythe, Grant; Taylor, Charles; Guerrier, Thomas; Launay, David; Mitra, Suman; Piehler, Jacob ; Molina-Paris, Carmen; Moraga, Ignacio
1092021Biomolecule sensing in THz range with n-Ge/Si antennasChavarin, Carlos Alvarado; Wiciak, A. A.; Hardt, Elena; Gruessing, Soenke; Skibitzki, Oliver; Costina, Ioan; Seifert, Winfried; Klesse, Wolfgang M.; Manganelli, C. L.; You, Changjiang ; Flesch, Julia; Piehler, Jacob ; Missori, Mauro; Koczorowski, W.; Baldassarre, Leonetta; Witzigmann, Bernd; Capellini, Giovanni; Spirito, Davide
1102021Dissociation of β2m from MHC Class I Triggers Formation of Noncovalent, Transient Heavy Chain DimersDirscherl, Cindy; S, Loechte; Hein, Zeynep; Kopicki, Janine-Denise; Ar, Harders; N, Linden; Weghuber, Julian; Garcia-Alai, Maria; Uetrecht, Charlotte; Zacharias, Martin; Piehler, Jacob ; Lanzerstorfer, Peter; Springer, Sebastian
1112021Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitorsCui, Lu; Moraga, Ignacio; Lerbs, Tristan; Van Neste, Camille; Wilmes, Stephan; Tsutsumi, Naotaka; Trotman-Grant, Aaron Claudius; Gakovic, Milica; Andrews, Sarah; Gotlib, Jason; Darmanis, Spyros; Enge, Martin; Quake, Stephen; Hitchcock, Ian S.; Piehler, Jacob ; Garcia, K. Christopher; Wernig, Gerlinde
1122021Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the GolgiSchoppe, Jannis; Schubert, Evelyn; Apelbaum, Amir; Yavavli, Erdal; Birkholz, Oliver; Stephanowitz, Heike; Han, Yaping; Perz, Angela; Hofnagel, Oliver; Liu, Fan; Piehler, Jacob ; Raunser, Stefan; Ungermann, Christian 
1132021TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNAKaur, Parminder; Barnes, Ryan; Pan, Hai; Detwiler, Ariana C.; Liu, Ming; Mahn, Chelsea; Hall, Jonathan; Messenger, Zach; You, Changjiang ; Piehler, Jacob ; Smart, Robert C.; Riehn, Robert; Opresko, Patricia L.; Wang, Hong
1142021Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of actionKast, Florian; Schwill, Martin; Stueber, Jakob C.; Pfundstein, Svende; Nagy-Davidescu, Gabriela; Rodriguez, Josep M. Monne; Seehusen, Frauke; Richter, Christian P.; Honegger, Annemarie; Hartmann, Karen Patricia; Weber, Thomas G.; Kroener, Felix; Ernst, Patrick; Piehler, Jacob ; Pluckthun, Andreas
1152021Diffraction-Unlimited Photomanipulation at the Plasma Membrane via Specifically Targeted Upconversion NanoparticlesDrees, Christoph; Ruehl, Philipp; Czerny, Jacqueline; Chandra, Gemini; Bajorath, Janosch; Haase, Markus ; Heinemann, Stefan H.; Piehler, Jacob 
1162021IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon-induced JAK-STAT signaling and activating STATsShemesh, Maya; Lochte, Sara; Piehler, Jacob ; Schreiber, Gideon
1172021n-type Ge/Si antennas for THz sensingChavarin, C. A.; Hardt, E.; Gruessing, S.; Skibitzki, O.; Costina, I; Spirito, D.; Seifert, W.; Klesse, W.; Manganelli, C. L.; You, C. ; Flesch, J.; Piehler, J. ; Missori, M.; Baldassarre, L.; Witzigmann, B.; Capellini, G.
1182021Biofunctionalization of carbon nanotubes for reversible site-specific protein immobilizationJorde, Lara; Li, Zehao; Poeppelwerth, Adrian; Piehler, Jacob ; You, Changjiang ; Meyer, Carola 
1192021Four-Color Single-Molecule Imaging with Engineered Tags Resolves the Molecular Architecture of Signaling Complexes in the Plasma MembraneBellón, Junel Sotolongo; Birkholz, Oliver; Richter, Christian; Eull, Florian; Kenneweg, Hella; Wilmes, Stephan; Rothbauer, Ulrich; You, Changjiang ; Walter, Mark R.; Kurre, Rainer ; Piehler, Jacob 
1202021Dissociation of β2m from cell surface MHC class I triggers formation of noncovalent, transient heavy chain dimersSpringer, Sebastian; Dirscherl, Cindy; Löchte, Sara; Hein, Zeynep; Kopicki, Janine-Denise; Harders, Antonia; Linden, Noemi; Weghuber, Julian; Garcia-Alai, Maria; Uetrecht, Charlotte; Zacharias, Martin; Lanzerstorfer, Peter; Piehler, Jacob